Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 8/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335456 | 1.00 | CTSK (0.51) | CTSKRENPSMB1CTSLCTSB | |
| SCHEMBL7337224 | 1.00 | CTSK (0.51) | CTSKRENPSMB1CTSLCTSB | |
| SCHEMBL7335470 | 1.00 | CTSK (0.51) | CTSKRENPSMB1CTSLCTSB | |
| SCHEMBL7340230 | 0.85 | CTSK (0.56) | CTSKRENPSMB1CTSLCTSB | |
| SCHEMBL7338539 | 0.82 | CTSK (0.59) | CTSKPSMB1CTSLCTSBCAPN1 | |
| SCHEMBL7338528 | 0.82 | CTSK (0.59) | CTSKPSMB1CTSLCTSBCAPN1 | |
| SCHEMBL7342219 | 0.82 | REN (0.44) | CTSKRENCTSL | |
| SCHEMBL7342207 | 0.82 | REN (0.44) | CTSKRENCTSL | |
| SCHEMBL7342193 | 0.82 | REN (0.44) | CTSKRENCTSL | |
| SCHEMBL7347430 | 0.81 | CTSK (0.51) | CTSKRENPSMB1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |