Sugi Predict

Sugi Predict / Compounds / SCHEMBL7342193

SCHEMBL7342193

SCHEMBL7342193

CCCC/C=C\c1c([C@H](O)[C@H](CCCC)NC(=O)[C@H](CC(C)C)NC(=O)OCC2CCCCC2)c1=O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 4/20 0.44
▸ CTSL P07711 6/20 0.43
▸ CTSK P43235 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7342207 1.00 REN (0.44) RENCTSLCTSK
SCHEMBL7342219 1.00 REN (0.44) RENCTSLCTSK
SCHEMBL7334867 0.87 CTSK (0.47) RENCTSLCTSK
SCHEMBL7334877 0.87 CTSK (0.47) RENCTSLCTSK
SCHEMBL7342199 0.84 CTSK (0.45) RENCTSLCTSK
SCHEMBL7342190 0.84 CTSK (0.45) RENCTSLCTSK
SCHEMBL7335470 0.82 CTSK (0.51) RENCTSLCTSK
SCHEMBL7344926 0.82 REN (0.51) RENCTSLCTSK
SCHEMBL7335474 0.82 CTSK (0.51) RENCTSLCTSK
SCHEMBL7335456 0.82 CTSK (0.51) RENCTSLCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5416117-A Protease inhibitor MITSUBISHI KASEI CORPORATION (JP) 1995-05-16 — — US disclosed
EP-0520427-B1 Cyclopropenone derivatives MITSUBISHI CHEM IND (JP) 1994-12-14 — — EP disclosed
US-5328909-A Protease inhibitors MITSUBISHI KASEI CORPORATION (JP) 1994-07-12 — — US disclosed
EP-0520427-A1 Cyclopropenone derivatives Mitsubishi Chemical Corporation (JP) 1992-12-30 — — EP disclosed