Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342536 | 0.89 | KMT2A (0.44) | KMT2AMLNRNR1I2NR3C1PGR | |
| SCHEMBL7368737 | 0.88 | RAB9A (0.43) | KMT2AMLNRNR1I2NR3C1PGR | |
| SCHEMBL7342936 | 0.87 | SGMS2 (0.51) | KMT2AMLNRNR1I2NR3C1PGR | |
| SCHEMBL7376574 | 0.86 | AVPR2 (0.42) | KMT2AMLNRNR1I2NR3C1PGR | |
| SCHEMBL7374760 | 0.85 | AVPR2 (0.43) | KMT2AMLNRNR1I2NR3C1PGR | |
| SCHEMBL7336962 | 0.84 | MAPT (0.50) | KMT2AMLNRNR1I2NR3C1PGR | |
| SCHEMBL7372350 | 0.83 | AVPR2 (0.43) | KMT2AAVPR2ALDH1A1LMNARAB9A | |
| SCHEMBL7343269 | 0.82 | AVPR2 (0.41) | KMT2AMLNRNR1I2NR3C1PGR | |
| SCHEMBL7370807 | 0.82 | KMT2A (0.45) | KMT2AMLNRNR1I2NR3C1PGR | |
| SCHEMBL7345310 | 0.82 | KMT2A (0.44) | KMT2AMLNRNR1I2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |