Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | YAP1 | P46937 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348694 | 0.93 | PPARG (0.48) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7340760 | 0.92 | CACNA1B (0.50) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7343410 | 0.92 | FAAH (0.50) | PPARGKDM4ECACNA1BALDH1A1SMN1; SMN2 | |
| SCHEMBL7339837 | 0.92 | PPARG (0.47) | PPARGPOLBL3MBTL1KDM4EMME | |
| SCHEMBL7341214 | 0.91 | PPARG (0.47) | PPARGL3MBTL1MAPTMMEACE | |
| SCHEMBL7338702 | 0.91 | PPARG (0.47) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7347985 | 0.90 | YAP1 (0.50) | PPARGPOLBCACNA1BYAP1 | |
| SCHEMBL7337879 | 0.90 | PPARG (0.45) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7341683 | 0.90 | PPARG (0.45) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL7343476 | 0.90 | YAP1 (0.47) | PPARGACECACNA1BYAP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |