Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 7/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | FPR2 | P25090 | 3/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348694 | 0.92 | PPARG (0.48) | CACNA1BPPARGYAP1ACEMME | |
| SCHEMBL7335997 | 0.92 | PPARG (0.50) | CACNA1BPPARGYAP1ACEMME | |
| SCHEMBL7345173 | 0.92 | CALCRL (0.50) | CACNA1BPPARGYAP1 | |
| SCHEMBL7343533 | 0.92 | PPARG (0.45) | CACNA1BDPP7PPARGYAP1ACE | |
| SCHEMBL7338702 | 0.91 | PPARG (0.47) | CACNA1BDPP7PPARGYAP1ACE | |
| SCHEMBL7341214 | 0.91 | PPARG (0.47) | PPARGYAP1ACEMMECPA1 | |
| SCHEMBL7339837 | 0.91 | PPARG (0.47) | CACNA1BPPARGYAP1ACEMME | |
| SCHEMBL7343476 | 0.91 | YAP1 (0.47) | CACNA1BPPARGYAP1ACE | |
| SCHEMBL7343410 | 0.91 | FAAH (0.50) | CACNA1BPPARG | |
| SCHEMBL7347680 | 0.89 | MEN1 (0.46) | CACNA1BPPARGYAP1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |