Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345983 | 0.87 | MAPT (0.58) | ALDH1A1MAPTRAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL7336895 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTRAB9ANPC1GAA | |
| SCHEMBL7378000 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTRAB9ANPC1GAA | |
| SCHEMBL7340419 | 0.82 | TP53 (0.51) | ALDH1A1MAPTRAB9ANPC1GAA | |
| SCHEMBL7344448 | 0.81 | PYGL (0.58) | ALDH1A1MAPTRAB9ANPC1GAA | |
| SCHEMBL8636243 | 0.79 | BRD4 (0.49) | ALDH1A1RAB9ANPC1GAATP53 | |
| SCHEMBL7342516 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTRAB9ANPC1GAA | |
| SCHEMBL7345419 | 0.78 | TP53 (0.44) | ALDH1A1MAPTRAB9ANPC1GAA | |
| SCHEMBL7337480 | 0.78 | TP53 (0.42) | ALDH1A1MAPTRAB9ANPC1GAA | |
| SCHEMBL7427909 | 0.77 | TP53 (0.43) | ALDH1A1MAPTRAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |