Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340419 | 0.91 | TP53 (0.51) | BRD4MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8636250 | 0.83 | BRD4 (0.51) | BRD4MEN1KMT2AKDM4ESMPD1 | |
| SCHEMBL7344583 | 0.81 | TP53 (0.40) | BRD4MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7341146 | 0.80 | BRD4 (0.49) | BRD4MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7336189 | 0.79 | ALDH1A1 (0.50) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7337754 | 0.78 | BRD4 (0.47) | BRD4MEN1KMT2AKDM4EGAA | |
| SCHEMBL7338658 | 0.77 | BRD4 (0.56) | BRD4MEN1KMT2ARAB9AGAA | |
| SCHEMBL7342054 | 0.77 | TP53 (0.44) | BRD4MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7337480 | 0.77 | TP53 (0.42) | BRD4MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7339795 | 0.77 | SGMS2 (0.57) | BRD4MEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |