Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332593 | 0.88 | CYP1A2 (0.40) | PTGS2PTGESALOX5PSEN1DRD1 | |
| SCHEMBL7334308 | 0.81 | PTGS2 (0.43) | PTGS2PTGESALOX5PSEN1DRD1 | |
| SCHEMBL8081374 | 0.81 | SMN1; SMN2 (0.46) | CAMK2AEGLN2EGLN1BRS3LMNA | |
| SCHEMBL8092961 | 0.77 | KDM4E (0.45) | CAMK2ANPSR1KDM4EMEN1MAPT | |
| SCHEMBL8092956 | 0.75 | KDM4E (0.40) | CAMK2ANPSR1KDM4EMEN1S1PR2 | |
| SCHEMBL4611564 | 0.75 | CXCL8 (0.56) | CAMK2ACXCL8KDM4EMAPT | |
| SCHEMBL7333637 | 0.74 | CXCL8 (0.55) | NPSR1CXCL8MEN1S1PR2S1PR4 | |
| SCHEMBL8081337 | 0.73 | CAMK2A (0.56) | CAMK2ATHRBNPSR1CXCL8KDM4E | |
| SCHEMBL7340892 | 0.73 | RXRA (0.47) | PSEN1KDM4EMAPTHTTPPARG | |
| SCHEMBL7344505 | 0.73 | CXCL8 (0.44) | CAMK2ANPSR1CXCL8KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968938-A | Piperazine oxytocin receptor antagonists | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |