Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653909 | 0.94 | HCRTR2 (0.44) | HCRTR2KMT2AHSD17B10USP2MAPT | |
| SCHEMBL1495969 | 0.85 | TP53 (0.52) | KMT2AMAPTALDH1A1PTGER1L3MBTL1 | |
| SCHEMBL4867236 | 0.82 | LMNA (0.41) | HCRTR2KMT2AHSD17B10MAPTKDM4E | |
| SCHEMBL14408832 | 0.72 | TSHR (0.54) | HSD17B10USP2KDM4EALDH1A1ALOX5 | |
| SCHEMBL25333728 | 0.72 | PSEN1 (0.43) | HCRTR2KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL23209700 | 0.72 | MMP1 (0.46) | HCRTR2MAPTALDH1A1PTGER1L3MBTL1 | |
| SCHEMBL1291299 | 0.72 | PSEN1 (0.51) | HCRTR2MAPTL3MBTL1TP53 | |
| SCHEMBL28331917 | 0.69 | CA12 (0.49) | HSD17B10USP2ALDH1A1CA9 | |
| SCHEMBL6541841 | 0.69 | L3MBTL1 (0.63) | ALOX5CA1CA2CA5ACA9 | |
| SCHEMBL9037934 | 0.68 | KMT2A (0.51) | KMT2AHSD17B10MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |