Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | NQO1 | P15559 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5900962 | 0.80 | CYP1A2 (0.60) | ALOX5CYP1A2CYP2A6KMT2ACYP2D6 | |
| SCHEMBL2838141 | 0.80 | CYP1A2 (0.65) | ALOX5CYP1A2CYP2A6KMT2ACYP2D6 | |
| SCHEMBL6947008 | 0.79 | PTPN1 (0.55) | ALOX5MEN1KMT2APTPN1CRHBP | |
| SCHEMBL35308 | 0.78 | PTPN1 (0.61) | MEN1KMT2APTPN1CRHBPCRHR2 | |
| SCHEMBL18482937 | 0.77 | CYP2A6 (0.58) | ALOX5CYP1A2CYP2A6CYP2D6NFKB1 | |
| SCHEMBL28846677 | 0.76 | CYP1A2 (0.60) | ALOX5CYP1A2CYP2A6KMT2ACYP2D6 | |
| SCHEMBL598561 | 0.74 | CYP1A2 (0.58) | ALOX5CYP1A2CYP2A6KMT2ACYP2D6 | |
| SCHEMBL29417927 | 0.74 | CYP1A2 (0.58) | ALOX5CYP1A2CYP2A6KMT2ACYP2D6 | |
| SCHEMBL28256206 | 0.74 | ALOX5 (0.53) | ALOX5CYP1A2CYP2A6MEN1KMT2A | |
| SCHEMBL4653640 | 0.74 | ALOX5 (0.62) | ALOX5CETPCYP1A2CYP2A6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110963-A | FOR PROPHYLAXIS AND TREATMENT OF INSULIN RESISTANCE, HYPERGLYCEMIA, TYPE II DIABETES, MOLULATING GLUCOSE LEVELS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |