Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.53 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337127 | 1.00 | CTSL (0.53) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7337277 | 0.91 | CTSK (0.59) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7337267 | 0.91 | CTSK (0.59) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7343193 | 0.90 | CTSK (0.50) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7343207 | 0.90 | CTSK (0.50) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7339587 | 0.90 | CTSK (0.50) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7339604 | 0.90 | CTSK (0.50) | CTSLCTSBCTSSCTSK | |
| SCHEMBL10802556 | 0.78 | CTSL (0.70) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL19807564 | 0.78 | TACR1 (0.72) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7344977 | 0.78 | CTSK (0.57) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |