Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339587 | 1.00 | CTSK (0.50) | CTSKPSMB8PSMB9PSMB5CYP1A2 | |
| SCHEMBL7343193 | 1.00 | CTSK (0.50) | CTSKPSMB8PSMB9PSMB5CYP1A2 | |
| SCHEMBL7343207 | 1.00 | CTSK (0.50) | CTSKPSMB8PSMB9PSMB5CYP1A2 | |
| SCHEMBL7337127 | 0.90 | CTSL (0.53) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7337140 | 0.90 | CTSL (0.53) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7337277 | 0.89 | CTSK (0.59) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7337267 | 0.89 | CTSK (0.59) | CTSKCTSSCTSLCTSB | |
| SCHEMBL8399100 | 0.78 | ADORA3 (0.35) | ELANE | |
| SCHEMBL10706457 | 0.78 | CTSK (0.55) | CTSKCYP1A2CTSSCTSLCTSB | |
| SCHEMBL11515552 | 0.75 | CTSK (0.63) | CTSKCYP1A2CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |