Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | YAP1 | P46937 | 2/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342635 | 0.91 | GPR132 (0.49) | PTPN1BCL2YAP1CTSL | |
| SCHEMBL7342642 | 0.91 | GPR132 (0.49) | PTPN1BCL2YAP1CTSL | |
| SCHEMBL7342692 | 0.90 | PTPN1 (0.57) | PTPN1BCL2YAP1ITGB3ITGA2B | |
| SCHEMBL7342697 | 0.90 | PTPN1 (0.57) | PTPN1BCL2YAP1ITGB3ITGA2B | |
| SCHEMBL7339216 | 0.89 | PTPN1 (0.46) | PTPN1BCL2MDM4TP53HDAC1 | |
| SCHEMBL7339224 | 0.89 | PTPN1 (0.46) | PTPN1BCL2MDM4TP53HDAC1 | |
| SCHEMBL31097655 | 0.86 | HDAC8 (0.49) | PTPN1MDM4TP53 | |
| SCHEMBL7338800 | 0.85 | MDM4 (0.48) | PTPN1MDM4TP53CTSSCTSK | |
| SCHEMBL1957887 | 0.85 | MDM4 (0.48) | PTPN1MDM4TP53CTSSCTSK | |
| SCHEMBL29351891 | 0.85 | MDM4 (0.48) | PTPN1MDM4TP53CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |