Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.43 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342635 | 1.00 | GPR132 (0.49) | GPR132PTPN1ACACBCMKLR2CMKLR1 | |
| SCHEMBL7337146 | 0.91 | PTPN1 (0.51) | PTPN1CTSLYAP1BCL2 | |
| SCHEMBL31688488 | 0.89 | GPR132 (0.63) | GPR132ACACBCMKLR2CMKLR1 | |
| SCHEMBL7339216 | 0.87 | PTPN1 (0.46) | GPR132PTPN1BCL2 | |
| SCHEMBL7339224 | 0.87 | PTPN1 (0.46) | GPR132PTPN1BCL2 | |
| SCHEMBL7342692 | 0.86 | PTPN1 (0.57) | PTPN1YAP1BCL2 | |
| SCHEMBL7342697 | 0.86 | PTPN1 (0.57) | PTPN1YAP1BCL2 | |
| SCHEMBL28741504 | 0.84 | MDM4 (0.52) | CTSLCTSBPOLBMAPTTDP1 | |
| SCHEMBL28741502 | 0.84 | MDM4 (0.52) | CTSLCTSBPOLBMAPTTDP1 | |
| SCHEMBL7345627 | 0.84 | PTPN1 (0.49) | PTPN1YAP1MAPTTDP1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |