Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 2/20 | 0.46 |
| ▸ | YAP1 | P46937 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342697 | 1.00 | PTPN1 (0.57) | PTPN1P2RX7BCL2YAP1ABCB1 | |
| SCHEMBL7337146 | 0.90 | PTPN1 (0.51) | PTPN1BCL2YAP1ITGB3ITGA2B | |
| SCHEMBL31097655 | 0.86 | HDAC8 (0.49) | PTPN1 | |
| SCHEMBL7342635 | 0.86 | GPR132 (0.49) | PTPN1BCL2YAP1 | |
| SCHEMBL7342642 | 0.86 | GPR132 (0.49) | PTPN1BCL2YAP1 | |
| SCHEMBL7339216 | 0.85 | PTPN1 (0.46) | PTPN1BCL2 | |
| SCHEMBL7339224 | 0.85 | PTPN1 (0.46) | PTPN1BCL2 | |
| SCHEMBL7338800 | 0.85 | MDM4 (0.48) | PTPN1CTSSCTSK | |
| SCHEMBL1957887 | 0.85 | MDM4 (0.48) | PTPN1CTSSCTSK | |
| SCHEMBL29351891 | 0.85 | MDM4 (0.48) | PTPN1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |