Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060249 | 0.81 | DHPS (0.66) | DHPS | |
| SCHEMBL7297617 | 0.76 | DHPS (0.58) | DHPS | |
| SCHEMBL28569633 | 0.74 | DHPS (0.72) | DHPS | |
| SCHEMBL28914005 | 0.73 | DHPS (0.73) | DHPS | |
| SCHEMBL28567652 | 0.73 | DHPS (0.73) | DHPS | |
| SCHEMBL5632559 | 0.73 | ALDH1A1 (0.48) | DHPS | |
| SCHEMBL28588146 | 0.72 | DHPS (0.74) | DHPS | |
| SCHEMBL7327716 | 0.68 | DHPS (0.45) | DHPS | |
| SCHEMBL5101462 | 0.68 | EDNRB (0.61) | DHPS | |
| SCHEMBL7851591 | 0.68 | DHPS (0.56) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526708-B1 | Sulfonamide, preparation and use thereof as medicine and intermediate | HOFFMANN LA ROCHE (CH) | 2000-10-18 | — | — | EP | disclosed |
| US-5292740-A | Sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0526708-A1 | Sulfonamide, preparation and use thereof as medicine and intermediate | F. HOFFMANN-LA ROCHE AG (CH) | 1993-02-10 | — | — | EP | disclosed |