Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 14/20 | 0.56 |
| ▸ | EDNRA | P25101 | 5/20 | 0.54 |
| ▸ | EDNRB | P24530 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060249 | 0.86 | DHPS (0.66) | DHPSEDNRAEDNRB | |
| SCHEMBL7851914 | 0.81 | EDNRA (0.49) | DHPSEDNRAEDNRB | |
| SCHEMBL5633773 | 0.80 | DHPS (0.56) | DHPSEDNRAEDNRB | |
| SCHEMBL4061140 | 0.80 | EDNRA (0.67) | DHPSEDNRAEDNRB | |
| SCHEMBL5631560 | 0.79 | DHPS (0.55) | DHPSEDNRAEDNRB | |
| SCHEMBL4066782 | 0.78 | DHPS (0.66) | DHPSEDNRAEDNRB | |
| SCHEMBL6584269 | 0.76 | DHPS (0.62) | DHPSEDNRAEDNRB | |
| SCHEMBL7853937 | 0.76 | DHPS (0.57) | DHPSEDNRAEDNRB | |
| SCHEMBL7298132 | 0.75 | EDNRA (0.76) | DHPSEDNRAEDNRB | |
| SCHEMBL4060942 | 0.75 | DHPS (0.56) | DHPSEDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713875-B1 | Sulfonamides | HOFFMANN LA ROCHE (CH) | 2001-03-21 | — | — | EP | claimed |