Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.59 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.58 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560660 | 0.91 | NPC1 (0.54) | ACHEAVPR2AVPR1ARAB9ANAMPT | |
| SCHEMBL8557890 | 0.88 | MEN1 (0.55) | AVPR2AVPR1ARAB9ANAMPT | |
| SCHEMBL8559349 | 0.87 | AVPR2 (0.60) | ACHEAVPR2AVPR1A | |
| SCHEMBL8563019 | 0.86 | AVPR2 (0.59) | ACHEAVPR2AVPR1ANAMPT | |
| SCHEMBL7369344 | 0.85 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL8560986 | 0.85 | LMNA (0.56) | AVPR2AVPR1ANAMPT | |
| SCHEMBL8560800 | 0.85 | AVPR2 (0.79) | AVPR2AVPR1A | |
| SCHEMBL8558993 | 0.85 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8556851 | 0.85 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL8557503 | 0.84 | ACHE (0.58) | ACHEHSD17B3AVPR2AVPR1ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |