Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 4/20 | 0.58 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.58 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.58 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341107 | 0.84 | PSMB11 (0.61) | HSPA5HSPA2HSPA1AHSPA9PSMB11 | |
| SCHEMBL7344263 | 0.82 | MEN1 (0.55) | IL1RNERAP2ERAP1MMEACE | |
| SCHEMBL7344077 | 0.82 | PPARG (0.60) | IL1RNERAP2ERAP1MMEACE | |
| SCHEMBL7336536 | 0.82 | LTA4H (0.59) | IL1RNERAP2ERAP1MMEACE | |
| SCHEMBL7345070 | 0.82 | HDAC8 (0.60) | IL1RNERAP2ERAP1HDAC6NPC1 | |
| SCHEMBL7348742 | 0.82 | LTA4H (0.59) | IL1RNERAP2ERAP1MMEACE | |
| SCHEMBL7337295 | 0.81 | HSPA5 (0.54) | HSPA5HSPA2HSPA1AHSPA9PKM | |
| SCHEMBL7337028 | 0.81 | PSMB1 (0.58) | IL1RNERAP2ERAP1MMEACE | |
| SCHEMBL7338318 | 0.81 | IL1RN (0.56) | IL1RNERAP2ERAP1MMEACE | |
| SCHEMBL7342789 | 0.81 | LTA4H (0.58) | IL1RNERAP2ERAP1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |