Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328500 | 0.93 | POLB (0.56) | KMT2AMEN1PDPK1ATMANPEP | |
| SCHEMBL7330045 | 0.93 | KMT2A (0.47) | KMT2AMEN1PDPK1ATMANPEP | |
| SCHEMBL7328371 | 0.90 | L3MBTL1 (0.62) | KMT2AMEN1POLBMRGPRX4NR4A2 | |
| SCHEMBL7331554 | 0.88 | F10 (0.56) | KMT2AMEN1PDPK1NR4A2CYP2C9 | |
| SCHEMBL7330976 | 0.88 | L3MBTL1 (0.53) | KMT2AMEN1MRGPRX4NR4A2L3MBTL1 | |
| SCHEMBL7330613 | 0.87 | F10 (0.52) | KMT2AMEN1PDPK1MRGPRX4L3MBTL1 | |
| SCHEMBL7330744 | 0.87 | L3MBTL1 (0.50) | KMT2AMEN1PDPK1ATMPOLB | |
| SCHEMBL13225823 | 0.87 | MRGPRX4 (0.53) | POLBTSHRMRGPRX4L3MBTL1MAPT | |
| SCHEMBL7331577 | 0.86 | F10 (0.53) | KMT2AMEN1PDPK1NR4A2 | |
| SCHEMBL7332190 | 0.85 | ATM (0.48) | KMT2AMEN1ATMANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | claimed |
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | disclosed |