Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CBX7 | O95931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328371 | 0.93 | L3MBTL1 (0.62) | L3MBTL1NR4A2KMT2AKCNH2MRGPRX4 | |
| SCHEMBL7337342 | 0.88 | KMT2A (0.52) | L3MBTL1NR4A2KMT2AMRGPRX4MEN1 | |
| SCHEMBL13225823 | 0.88 | MRGPRX4 (0.53) | L3MBTL1MRGPRX4NPC1ALDH1A1MAPT | |
| SCHEMBL7336104 | 0.87 | POLB (0.52) | L3MBTL1KMT2AMRGPRX4MEN1HSD11B1 | |
| SCHEMBL7335707 | 0.87 | L3MBTL1 (0.50) | L3MBTL1MRGPRX4TDP1NPC1MAPT | |
| SCHEMBL7330744 | 0.85 | L3MBTL1 (0.50) | L3MBTL1KMT2AMRGPRX4MEN1NPC1 | |
| SCHEMBL7328500 | 0.84 | POLB (0.56) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7333993 | 0.84 | L3MBTL1 (0.51) | L3MBTL1KMT2AMRGPRX4MEN1NPC1 | |
| SCHEMBL7330045 | 0.82 | KMT2A (0.47) | NR4A2KMT2AMRGPRX4MEN1 | |
| SCHEMBL7329854 | 0.81 | L3MBTL1 (0.62) | L3MBTL1NR4A2KMT2AMRGPRX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | claimed |
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | disclosed |