Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 4/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339650 | 0.88 | HTT (0.39) | MAPK1MAPTITGB3ITGA2BHTT | |
| SCHEMBL7340337 | 0.86 | ITGB3 (0.41) | MAPK1MAPTITGB3ITGA2BHTT | |
| SCHEMBL7344043 | 0.84 | ITGB3 (0.47) | MAPTITGB3ITGA2BHTTPKM | |
| SCHEMBL7343660 | 0.84 | ITGB3 (0.40) | MAPTITGB3ITGA2BHTTITGAV | |
| SCHEMBL7340669 | 0.83 | F10 (0.43) | MAPTITGB3ITGA2BHTTITGAV | |
| SCHEMBL7339620 | 0.83 | ITGB3 (0.41) | MAPTITGB3ITGA2BHTTITGAV | |
| SCHEMBL7341988 | 0.82 | L3MBTL1 (0.45) | MAPTITGB3ITGA2BHTTITGAV | |
| SCHEMBL7349763 | 0.81 | ITGB3 (0.48) | MAPTITGB3ITGA2BITGAVITGB1 | |
| SCHEMBL7348081 | 0.81 | ITGB3 (0.43) | MAPTITGB3ITGA2BHTTITGAV | |
| SCHEMBL4336179 | 0.81 | SMN1; SMN2 (0.41) | MAPTITGB3ITGA2BHTTITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |