Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 5/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343660 | 0.85 | ITGB3 (0.40) | F10ITGB3ITGA2BITGAVHTT | |
| SCHEMBL7337396 | 0.83 | MAPK1 (0.41) | F10ITGB3ITGA2BITGAVHTT | |
| SCHEMBL7339620 | 0.82 | ITGB3 (0.41) | F10ITGB3ITGA2BITGAVHTT | |
| SCHEMBL7348081 | 0.81 | ITGB3 (0.43) | F10ITGB3ITGA2BITGAVHTT | |
| SCHEMBL7343459 | 0.80 | KCNK3 (0.40) | F10ITGB3ITGA2BITGAVHTT | |
| SCHEMBL7339858 | 0.80 | ITGB3 (0.41) | F10ITGB3ITGA2BITGAVHTT | |
| SCHEMBL4336179 | 0.80 | SMN1; SMN2 (0.41) | F10ITGB3ITGA2BITGAVHTT | |
| SCHEMBL7347208 | 0.80 | SMN1; SMN2 (0.41) | F10ITGB3ITGA2BITGAVHTT | |
| SCHEMBL7348024 | 0.80 | ITGB3 (0.42) | F10ITGB3ITGA2BITGAVHTT | |
| SCHEMBL7341988 | 0.80 | L3MBTL1 (0.45) | F10ITGB3ITGA2BITGAVHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | disclosed |