Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709144 | 0.94 | BCHE (0.65) | GAANPC1RAB9ABCHECYP2D6 | |
| SCHEMBL5137719 | 0.92 | BCHE (0.63) | GAANPC1RAB9ABCHECYP2D6 | |
| Hydrochloric Acid SCHEMBL710872 | 0.91 | BCHE (0.61) | GAANPC1RAB9ABCHECYP2D6 | |
| Hydrochloric Acid SCHEMBL710873 | 0.91 | BCHE (0.61) | GAANPC1RAB9ABCHECYP2D6 | |
| SCHEMBL707879 | 0.83 | BCHE (0.73) | GAANPC1RAB9ABCHECYP2D6 | |
| Hydrochloric Acid SCHEMBL710645 | 0.80 | BCHE (0.69) | GAANPC1RAB9ABCHECYP2D6 | |
| Hydrochloric Acid SCHEMBL710646 | 0.80 | BCHE (0.69) | GAANPC1RAB9ABCHECYP2D6 | |
| SCHEMBL17200183 | 0.78 | BCHE (0.65) | GAANPC1RAB9ABCHECYP2D6 | |
| SCHEMBL2673648 | 0.78 | LMNA (0.63) | GAANPC1RAB9ABCHECYP2D6 | |
| SCHEMBL370724 | 0.77 | BCHE (0.86) | GAANPC1RAB9ABCHECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598962-B1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH AS (DK) | 1999-02-17 | — | — | EP | claimed |
| EP-0598962-B1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH AS (DK) | 1999-02-17 | — | — | EP | disclosed |
| EP-0598962-A1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-06-01 | — | — | EP | disclosed |
| US-5296493-A | Analgesics or antiischemics | NEUROSEARCH A/S (DK) | 1994-03-22 | — | — | US | disclosed |