Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EML4 | Q9HC35 | 5/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.35 |
| ▸ | RET | P07949 | 5/20 | 0.35 |
| ▸ | ROS1 | P08922 | 5/20 | 0.35 |
| ▸ | FLT3 | P36888 | 5/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7339240 | 0.91 | ITGB3 (0.51) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7347695 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7343054 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7339244 | 0.84 | KDM4E (0.40) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7339516 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7337291 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7347536 | 0.81 | ITGB3 (0.63) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7347541 | 0.80 | ITGB3 (0.50) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7344932 | 0.78 | ITGB3 (0.49) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7343064 | 0.78 | GAA (0.39) | ITGB3ITGA2BALOX15KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |