Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346577 | 0.95 | ITGB3 (0.52) | ITGB3ITGA2BALOX15HRH3UBE2T | |
| Trifluoroacetic Acid SCHEMBL7339460 | 0.89 | ITGB3 (0.63) | ITGB3ITGA2BALOX15HRH3UBE2T | |
| SCHEMBL7339480 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BALOX15HRH3UBE2T | |
| Trifluoroacetic Acid SCHEMBL7339240 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7342470 | 0.84 | HRH3 (0.44) | ITGB3ITGA2BALOX15HRH3CXCR3 | |
| SCHEMBL7342461 | 0.84 | HRH3 (0.44) | ITGB3ITGA2BALOX15HRH3CXCR3 | |
| Trifluoroacetic Acid SCHEMBL7344936 | 0.84 | PPARG (0.36) | ITGB3ITGA2BALOX15HRH3CXCR3 | |
| Trifluoroacetic Acid SCHEMBL7342136 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BALOX15HRH3KDM4E | |
| Trifluoroacetic Acid SCHEMBL7339516 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7345703 | 0.82 | ITGB3 (0.71) | ITGB3ITGA2BALOX15HRH3UBE2T |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |