Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 3/20 | 0.33 |
| ▸ | ROS1 | P08922 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343064 | 0.95 | GAA (0.39) | KDM4EALDH1A1GAAALOX12SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7339521 | 0.91 | KDM4E (0.39) | KDM4EALDH1A1GAAALOX12SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7347549 | 0.91 | ITGB3 (0.43) | KDM4EALDH1A1GAAALOX12SMN1; SMN2 | |
| SCHEMBL7338006 | 0.85 | GAA (0.37) | KDM4EALDH1A1GAAALOX12SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7344936 | 0.85 | PPARG (0.36) | KDM4EALDH1A1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL7337811 | 0.85 | ITGB3 (0.47) | KDM4EALDH1A1GAAALOX12SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7337491 | 0.84 | ITGB3 (0.42) | KDM4EALDH1A1GAAALOX12SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7339240 | 0.84 | ITGB3 (0.51) | KDM4EALDH1A1GAAALOX12SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7334117 | 0.83 | MEN1 (0.36) | KDM4EALDH1A1OPRM1OPRL1CDK9 | |
| SCHEMBL7345353 | 0.82 | ITGB3 (0.47) | KDM4EALDH1A1SMN1; SMN2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |