Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7337896 | 1.00 | GPR119 (0.48) | GPR119ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7345415 | 0.94 | GPR119 (0.53) | GPR119ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7347730 | 0.94 | GPR119 (0.53) | GPR119ITGB3ITGA2BF2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7337569 | 0.90 | ITGB3 (0.48) | GPR119ITGB3ITGA2BF2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7337566 | 0.90 | ITGB3 (0.48) | GPR119ITGB3ITGA2BF2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7338643 | 0.90 | ITGB3 (0.48) | GPR119ITGB3ITGA2BF2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7341384 | 0.88 | ITGB3 (0.45) | GPR119ITGB3ITGA2BF2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7341388 | 0.88 | ITGB3 (0.45) | GPR119ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7341394 | 0.85 | GPR119 (0.41) | GPR119ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7337907 | 0.82 | ITGB3 (0.53) | GPR119ITGB3ITGA2BF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |