Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7337569 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7337566 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7337902 | 0.94 | ITGB3 (0.53) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7337907 | 0.94 | ITGB3 (0.53) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7337896 | 0.90 | GPR119 (0.48) | ITGB3ITGA2BGPR119F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7337888 | 0.90 | GPR119 (0.48) | ITGB3ITGA2BGPR119F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7339210 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7342546 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7339218 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7344123 | 0.88 | ITGB3 (0.45) | ITGB3ITGA2BALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |