Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.62 |
| ▸ | ITGAV | P06756 | 16/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360585 | 0.78 | ITGB3 (0.72) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL7398842 | 0.77 | ITGB3 (0.64) | ITGB3ITGAVITGA2B | |
| SCHEMBL8468930 | 0.77 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7917702 | 0.77 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL8327959 | 0.76 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7442340 | 0.76 | ITGB3 (0.59) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL7368305 | 0.75 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL6951803 | 0.73 | ITGB3 (0.73) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL6947538 | 0.72 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL6941347 | 0.72 | ITGB3 (1.00) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |