Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.60 |
| ▸ | ITGAV | P06756 | 17/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078805 | 0.78 | TSHR (0.43) | ITGB3ITGAVITGA2BTP53MAPT | |
| SCHEMBL7338175 | 0.75 | ITGB3 (0.62) | ITGB3ITGAVITGA2B | |
| SCHEMBL7398023 | 0.75 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7367179 | 0.75 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7368298 | 0.75 | ITGB3 (0.59) | ITGB3ITGAVITGA2BMETTL3METTL14 | |
| SCHEMBL7360585 | 0.72 | ITGB3 (0.72) | ITGB3ITGAVITGA2B | |
| SCHEMBL7401266 | 0.72 | TSHR (0.43) | ITGB3ITGA2BTP53 | |
| SCHEMBL7919242 | 0.72 | TSHR (0.43) | ITGB3ITGA2BTP53 | |
| SCHEMBL7368068 | 0.71 | CDK4 (0.51) | — | |
| SCHEMBL5785504 | 0.71 | SSTR3 (0.60) | ITGB3ITGAVMETTL3METTL14SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | claimed |