Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335512 | 0.88 | DCTPP1 (0.43) | DCTPP1ALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL7338080 | 0.87 | DCTPP1 (0.42) | DCTPP1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL7332307 | 0.84 | DCTPP1 (0.49) | DCTPP1CYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL7339811 | 0.75 | DCTPP1 (0.43) | DCTPP1CYP3A4ALDH1A1HPGDHDAC8 | |
| SCHEMBL7338245 | 0.73 | DCTPP1 (0.49) | DCTPP1CYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL7337608 | 0.67 | RAB9A (0.43) | ALDH1A1HPGDMAPTHSD17B10TDP1 | |
| Methane SCHEMBL7899065 | 0.65 | DCTPP1 (0.40) | DCTPP1 | |
| SCHEMBL7166244 | 0.65 | IDO1 (0.44) | MAPTCYP2D6IDO1TDO2HPGDS | |
| SCHEMBL7327647 | 0.64 | MAPT (0.44) | DCTPP1CYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL3880444 | 0.64 | TRPA1 (0.39) | CYP2C19CYP2D6IDO1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | claimed |
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | disclosed |