Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361407 | 0.89 | PKM (0.48) | PKMLTA4HGAAALDH1A1TEAD3 | |
| SCHEMBL16698725 | 0.79 | PKM (0.53) | PKMLTA4HGAAALDH1A1TEAD3 | |
| SCHEMBL1446252 | 0.77 | LTA4H (0.50) | PKMLTA4HGAAALDH1A1TEAD3 | |
| SCHEMBL25035706 | 0.77 | PKM (0.56) | PKMLTA4HGAAALDH1A1TEAD3 | |
| SCHEMBL3019770 | 0.72 | PKM (0.49) | PKMLTA4HGAAALDH1A1TEAD3 | |
| SCHEMBL9864517 | 0.72 | GSK3A (0.61) | PKMLTA4HGAAALDH1A1TEAD3 | |
| SCHEMBL7279696 | 0.71 | PKM (0.63) | PKMLTA4HGAAALDH1A1MAPT | |
| SCHEMBL27363764 | 0.70 | PKM (0.56) | PKMLTA4HGAAALDH1A1TEAD3 | |
| SCHEMBL21911636 | 0.70 | PKM (0.44) | PKMLTA4HGAAALDH1A1TEAD3 | |
| SCHEMBL9145422 | 0.70 | PKM (0.52) | PKMLTA4HGAAALDH1A1TEAD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726898-B1 | PHENYLINDOLE COMPOUNDS | LUNDBECK & CO AS H (DK) | 2000-12-20 | — | — | EP | disclosed |
| US-5703087-A | PSYCHOLOGICAL DISORDERS | H. LUNDBECK A/S (DK) | 1997-12-30 | — | — | US | disclosed |
| EP-0726898-A1 | PHENYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012591-A1 | PHENYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-05-11 | — | — | WO | disclosed |