Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232932 | 0.98 | DPP7 (0.39) | DPP7FDPSL3MBTL1LMNAGAA | |
| SCHEMBL7369696 | 0.79 | KDM4E (0.42) | LMNAMMP1MMP3 | |
| SCHEMBL8809418 | 0.79 | OPRD1 (0.39) | — | |
| SCHEMBL11682805 | 0.76 | ALDH1A1 (0.40) | LMNAGAAEPHX1 | |
| SCHEMBL27321259 | 0.75 | DPP7 (0.45) | DPP7FDPSLMNAGAA | |
| SCHEMBL11681642 | 0.75 | ALDH1A1 (0.40) | L3MBTL1LMNAGAA | |
| SCHEMBL6243407 | 0.72 | DPP7 (0.42) | DPP7FDPSL3MBTL1LMNAGAA | |
| SCHEMBL4783310 | 0.72 | DPP7 (0.42) | DPP7FDPSL3MBTL1LMNAGAA | |
| SCHEMBL10509650 | 0.72 | DPP7 (0.42) | DPP7FDPSL3MBTL1LMNAGAA | |
| SCHEMBL19517200 | 0.70 | ATM (0.41) | DPP7FDPSLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820453-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0820453-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5578633-A | VASOPRESSIN AND OXYTOCIN ANTAGONISTS | SANOFI (FR) | 1996-11-26 | — | — | US | disclosed |
| WO-1996031504-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1996-10-10 | — | — | WO | disclosed |
| US-5481005-A | N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present | SANOFI (FR) | 1996-01-02 | — | — | US | disclosed |
| EP-0673924-A1 | PROPIONIC ACID DERIVATIVE | TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5397801-A | Affinity for vasopressin and ocytocin receptors; disorders of nervous, cardiovascular and gastrointestinal systems | SANOFI (FR) | 1995-03-14 | — | — | US | disclosed |
| US-5338755-A | Have affinity for vasopressin and ocytocin receptors; intermediates for drugs that act on central nervous system | ELF SANOFI (FR) | 1994-08-16 | — | — | US | disclosed |