Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28852579 | 0.83 | KDM4E (0.55) | SLC2A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3272392 | 0.83 | SLC2A1 (0.54) | SLC2A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7339434 | 0.83 | SLC2A1 (0.54) | SLC2A1FOLH1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7802750 | 0.83 | SLC2A1 (0.54) | SLC2A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL360371 | 0.83 | CYP4F2 (0.63) | SLC2A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL5628566 | 0.81 | SLC2A1 (0.52) | SLC2A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9025608 | 0.80 | MTNR1A (0.52) | SLC2A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9826817 | 0.80 | MAOB (0.58) | SLC2A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19194585 | 0.80 | LTA4H (0.64) | SLC2A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19194551 | 0.80 | KDM4E (0.59) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781126-B1 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON SPA (IT) | 2001-12-12 | — | — | EP | disclosed |
| US-5674909-A | FOR TREATMENT OF CARDIOVASCULAR DISORDERS | ZAMBON GROUP (IT) | 1997-10-07 | — | — | US | disclosed |
| EP-0781126-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008228-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.P.A. (IT) | 1996-03-21 | — | — | WO | disclosed |