Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335872 | 0.89 | CA12 (0.45) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7337806 | 0.88 | CA12 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7336547 | 0.87 | MAPT (0.58) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4633394 | 0.82 | CTDSP1 (0.51) | LMNACYP1A2CYP3A4HPGDMAPT | |
| SCHEMBL7345259 | 0.79 | CYP4Z1 (0.51) | LMNARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL14311840 | 0.79 | CA12 (0.58) | CA1CA2CA12CA7CA9 | |
| SCHEMBL14311839 | 0.78 | CA1 (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL87450 | 0.77 | CA1 (0.83) | CA1CA2CA12CA7CA9 | |
| SCHEMBL14313816 | 0.76 | CA12 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5190217 | 0.76 | ALDH1A1 (0.70) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622984-A | INHIBITORS OF PHOSPHOLIPASE, VARIOUS PROTEASES | ONO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5432178-A | Substituted benzoic acid esters; use to prevent or treat inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis or multiple organ failure | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |