Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346077 | 0.90 | CYP4Z1 (0.45) | CYP4Z1MAPTCTDSP1LMNASMN1; SMN2 | |
| SCHEMBL7339360 | 0.88 | ALDH1A1 (0.52) | CYP4Z1MAPTCTDSP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7343255 | 0.88 | CYP4Z1 (0.44) | CYP4Z1MAPTCTDSP1LMNASMN1; SMN2 | |
| SCHEMBL4633394 | 0.80 | CTDSP1 (0.51) | MAPTCTDSP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7338657 | 0.79 | CA1 (0.53) | MAPTLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL68851 | 0.79 | CYP4Z1 (0.62) | CYP4Z1MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL512626 | 0.78 | CYP4Z1 (0.55) | CYP4Z1MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11077525 | 0.76 | CYP4Z1 (0.54) | CYP4Z1MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1803272 | 0.76 | CYP4Z1 (0.56) | CYP4Z1MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL17316726 | 0.75 | CYP4Z1 (0.52) | CYP4Z1MAPTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622984-A | INHIBITORS OF PHOSPHOLIPASE, VARIOUS PROTEASES | ONO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |