Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.37 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874561 | 0.86 | GAA (0.34) | CA1CA2KMT2APARP10 | |
| SCHEMBL7341358 | 0.85 | AKR1C1 (0.38) | CTSKALDH1A1KMT2ASLC6A3 | |
| SCHEMBL7347177 | 0.84 | HSD11B1 (0.36) | — | |
| SCHEMBL10658975 | 0.84 | HSD11B1 (0.36) | — | |
| SCHEMBL7342000 | 0.80 | HDAC3 (0.38) | CTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL7345830 | 0.78 | MAPT (0.42) | CES2CES1ALDH1A1KMT2AHPGD | |
| SCHEMBL11164078 | 0.77 | MMP14 (0.44) | KMT2A | |
| SCHEMBL15664683 | 0.77 | TET3 (0.42) | CA1CA2ALDH1A1TET3KMT2A | |
| SCHEMBL7342381 | 0.76 | HDAC3 (0.43) | CTSKALDH1A1KMT2AHPGDCYP2C19 | |
| SCHEMBL11091264 | 0.74 | NR4A2 (0.52) | ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316906-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |