Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339113 | 1.00 | MAOB (0.54) | MAOBPARP10LTA4HPGRADORA3 | |
| SCHEMBL7338844 | 0.84 | LTA4H (0.65) | MAOBLTA4HPTGS1LAP3 | |
| SCHEMBL7339057 | 0.84 | LTA4H (0.65) | MAOBLTA4HPTGS1LAP3 | |
| SCHEMBL7338836 | 0.84 | LTA4H (0.65) | MAOBLTA4HPTGS1LAP3 | |
| SCHEMBL561827 | 0.83 | MAOB (0.61) | MAOBPARP10LTA4HPGRADORA3 | |
| SCHEMBL561829 | 0.83 | MAOB (0.61) | MAOBPARP10LTA4HPGRADORA3 | |
| SCHEMBL7342898 | 0.82 | MAOB (0.52) | MAOBPARP10LTA4HALDH1A1RAB9A | |
| SCHEMBL7342884 | 0.82 | MAOB (0.52) | MAOBPARP10LTA4HALDH1A1RAB9A | |
| SCHEMBL7337394 | 0.81 | ACACB (0.56) | LTA4HALDH1A1SMN1; SMN2NPC1MAPK1 | |
| SCHEMBL7337381 | 0.81 | ACACB (0.56) | LTA4HALDH1A1SMN1; SMN2NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |