Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339144 | 1.00 | ACE (0.41) | ACERENF2PRSS1F10 | |
| SCHEMBL7335071 | 0.84 | AGTR2 (0.42) | ACELMNAAGTR2 | |
| SCHEMBL7330332 | 0.83 | F2 (0.36) | F2PRSS1F10LMNAPLAT | |
| SCHEMBL7335961 | 0.80 | BCL9 (0.38) | LMNA | |
| SCHEMBL8703107 | 0.72 | F2 (0.38) | F2PRSS1F10LMNAPLAT | |
| SCHEMBL58503 | 0.72 | HSD17B10 (0.50) | LMNA | |
| SCHEMBL9234487 | 0.72 | HSD17B10 (0.50) | LMNA | |
| SCHEMBL58198 | 0.72 | HSD17B10 (0.50) | LMNA | |
| SCHEMBL58523 | 0.72 | HSD17B10 (0.50) | LMNA | |
| SCHEMBL12201950 | 0.72 | HSD17B10 (0.50) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371091-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-12-06 | — | — | US | disclosed |