SCHEMBL7330332

C[C@@H]1CCN(C(=O)[C@H](CCCOS(C)(=O)=O)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)[C@@H](C(=O)O)C1

nearest known ligand 0.36

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	F2	P00734	4/20	0.36

▸	PRSS1	P07477	2/20	0.35

▸	F10	P00742	2/20	0.35

▸	LMNA	P02545	1/20	0.35

▸	PLAT	P00750	1/20	0.35

▸	PRSS2	P07478	1/20	0.35

▸	PRSS3	P35030	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7339153	0.83	ACE (0.41)	F2PRSS1F10LMNAPLAT
SCHEMBL7339144	0.83	ACE (0.41)	F2PRSS1F10LMNAPLAT
SCHEMBL7335071	0.74	AGTR2 (0.42)	LMNA
SCHEMBL7319267	0.72	ALDH1A1 (0.38)	LMNA
SCHEMBL7335961	0.71	BCL9 (0.38)	LMNA
SCHEMBL8703107	0.68	F2 (0.38)	F2PRSS1F10LMNAPLAT
SCHEMBL9234487	0.67	HSD17B10 (0.50)	LMNA
SCHEMBL58503	0.67	HSD17B10 (0.50)	LMNA
SCHEMBL14211002	0.67	HSD17B10 (0.50)	LMNA
SCHEMBL58523	0.67	HSD17B10 (0.50)	LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5371091-A	Anticoagulants	BRISTOL-MYERS SQUIBB COMPANY (US)	1994-12-06	—	—	US	disclosed