Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | CDK4 | P11802 | 3/20 | 0.35 |
| ▸ | CCND1 | P24385 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337098 | 0.95 | CDK1 (0.36) | CDK1CDK4CCND1CDK2SIGMAR1 | |
| SCHEMBL7340552 | 0.95 | CDK1 (0.36) | CDK1CDK4CCND1CDK2SIGMAR1 | |
| SCHEMBL7340457 | 0.93 | CDK1 (0.35) | CDK1CDK4CCND1CDK2DRD2 | |
| SCHEMBL7342217 | 0.92 | SIGMAR1 (0.37) | CDK1CDK4CCND1CDK2SIGMAR1 | |
| SCHEMBL7343781 | 0.92 | SIGMAR1 (0.35) | CDK1CDK4CCND1CDK2SIGMAR1 | |
| SCHEMBL8673452 | 0.91 | MEN1 (0.34) | SIGMAR1DRD2SUV39H2 | |
| SCHEMBL7778599 | 0.90 | SIGMAR1 (0.37) | CDK1CDK4CCND1CDK2SIGMAR1 | |
| SCHEMBL7347827 | 0.88 | MAPT (0.36) | DRD2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL7338860 | 0.87 | SIGMAR1 (0.37) | SIGMAR1DRD2SUV39H2MAPTAVPR2 | |
| SCHEMBL7345518 | 0.86 | SIGMAR1 (0.38) | CDK1CDK4CCND1CDK2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |