Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | DRD4 | P21917 | 4/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339161 | 0.91 | CDK1 (0.35) | DRD2SIGMAR1SUV39H2 | |
| SCHEMBL7337098 | 0.86 | CDK1 (0.36) | DRD2SIGMAR1SUV39H2 | |
| SCHEMBL7340552 | 0.86 | CDK1 (0.36) | MEN1KMT2ADRD2SIGMAR1SUV39H2 | |
| SCHEMBL7339013 | 0.85 | AVPR2 (0.38) | MEN1KMT2AEPHX2DRD2DRD4 | |
| SCHEMBL7340457 | 0.84 | CDK1 (0.35) | DRD2DRD4DRD3 | |
| SCHEMBL7342217 | 0.83 | SIGMAR1 (0.37) | MEN1KMT2AEPHX2DRD2SIGMAR1 | |
| SCHEMBL7343781 | 0.83 | SIGMAR1 (0.35) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL7778599 | 0.81 | SIGMAR1 (0.37) | MEN1KMT2ADRD2SIGMAR1SUV39H2 | |
| SCHEMBL7345595 | 0.79 | RXFP1 (0.34) | EPHX2DRD2SIGMAR1ALDH1A1 | |
| SCHEMBL7347827 | 0.79 | MAPT (0.36) | MEN1KMT2ADRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |