Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 4/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339373 | 1.00 | TPH1 (0.47) | TPH1SLC1A5SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL6505937 | 0.88 | ALDH1A1 (0.46) | KDM4EMEN1MAPTKMT2APDCD1 | |
| SCHEMBL29750308 | 0.82 | NOS3 (0.55) | SLC1A5ALPIPKMPTGS1XIAP | |
| SCHEMBL155234 | 0.82 | NOS3 (0.55) | SLC1A5ALPIPKMPTGS1XIAP | |
| SCHEMBL155235 | 0.82 | NOS3 (0.55) | SLC1A5ALPIPKMPTGS1XIAP | |
| SCHEMBL4595466 | 0.82 | NOS3 (0.55) | SLC1A5ALPIPKMPTGS1XIAP | |
| SCHEMBL5794030 | 0.81 | KDM4E (0.55) | TPH1PKMPTGS1SLC7A5GRIA2 | |
| SCHEMBL5794029 | 0.81 | KDM4E (0.55) | TPH1PKMPTGS1SLC7A5GRIA2 | |
| SCHEMBL29519833 | 0.81 | HSD17B10 (0.49) | PKMKDM4EMEN1LMNAMAPT | |
| SCHEMBL21803815 | 0.81 | SLC1A5 (0.47) | SLC1A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |