Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339635 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7339476 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7349543 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7341990 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7339492 | 0.77 | POLB (0.58) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7340688 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7342306 | 0.76 | MEN1 (0.56) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7349167 | 0.76 | RNF4 (0.59) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL7343019 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRPOLBRAB9A | |
| SCHEMBL15333880 | 0.73 | ALDH1A1 (0.46) | ALDH1A1RAB9ATRPM8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |