Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345723 | 0.94 | ITGB3 (0.49) | ITGB3ITGA2BALOX15KDM4EABL1 | |
| Trifluoroacetic Acid SCHEMBL7344936 | 0.89 | PPARG (0.36) | ITGB3ITGA2BALOX15KDM4EABL1 | |
| Trifluoroacetic Acid SCHEMBL7336173 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BALOX15KDM4EHRH3 | |
| SCHEMBL7346600 | 0.82 | MEN1 (0.37) | ITGB3ITGA2BALOX15KDM4EABL1 | |
| Trifluoroacetic Acid SCHEMBL7339460 | 0.82 | ITGB3 (0.63) | ITGB3ITGA2BALOX15KDM4EABL1 | |
| Trifluoroacetic Acid SCHEMBL7347549 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BALOX15KDM4E | |
| Trifluoroacetic Acid SCHEMBL7342491 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2BALOX15KDM4E | |
| SCHEMBL6839450 | 0.80 | ITGB3 (0.65) | ITGB3ITGA2BALOX15KDM4EHRH3 | |
| Methane SCHEMBL7337948 | 0.79 | ITGB3 (0.64) | ITGB3ITGA2BALOX15KDM4EHRH3 | |
| Hydrochloric Acid SCHEMBL8431413 | 0.78 | ALOX15 (0.64) | ITGB3ITGA2BALOX15KDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |