Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778679 | 0.89 | ALDH1A1 (0.44) | ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL7343339 | 0.89 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BSIGMAR1MAP3K7 | |
| SCHEMBL7778595 | 0.87 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BSIGMAR1MAP3K7 | |
| SCHEMBL7339781 | 0.87 | MAPT (0.38) | ADRA1DADRA1AADRA1BALDH1A1LMNA | |
| SCHEMBL7339388 | 0.86 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7342198 | 0.84 | RXFP1 (0.39) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7344642 | 0.84 | HDAC1 (0.43) | ALDH1A1 | |
| SCHEMBL7345510 | 0.84 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BSIGMAR1ALDH1A1 | |
| SCHEMBL7338852 | 0.83 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7344390 | 0.83 | RXFP1 (0.42) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |