Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339781 | 0.92 | MAPT (0.38) | ALDH1A1ADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL7344642 | 0.90 | HDAC1 (0.43) | ALDH1A1KMT2ANPSR1MAPK1NTSR1 | |
| SCHEMBL7339934 | 0.89 | AVPR2 (0.40) | ALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL7344390 | 0.88 | RXFP1 (0.42) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7337787 | 0.88 | ALDH1A1 (0.41) | ALDH1A1ADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL7347816 | 0.84 | TP53 (0.38) | ALDH1A1KMT2ANPSR1HTTSMN1; SMN2 | |
| SCHEMBL7345964 | 0.83 | LMNA (0.49) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL7346417 | 0.83 | TP53 (0.42) | KMT2ANPSR1HTTSMN1; SMN2MEN1 | |
| SCHEMBL7780810 | 0.83 | TP53 (0.42) | KMT2ANPSR1HTTSMN1; SMN2MEN1 | |
| SCHEMBL7342516 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KMT2ANPSR1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |