Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340481 | 0.90 | MPO (0.51) | MPODAGLASMN1; SMN2LMNARAB9A | |
| SCHEMBL7290997 | 0.81 | PKM (0.49) | SMN1; SMN2LMNARAB9AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7300661 | 0.81 | PKM (0.51) | SMN1; SMN2LMNARAB9AMAPTKDM4E | |
| SCHEMBL7300983 | 0.76 | PKM (0.48) | SMN1; SMN2LMNARAB9AMAPTKDM4E | |
| SCHEMBL7294735 | 0.73 | DAGLA (0.46) | MPODAGLASMN1; SMN2LMNARAB9A | |
| SCHEMBL1901781 | 0.73 | SMN1; SMN2 (0.61) | DAGLASMN1; SMN2LMNARAB9AMAPT | |
| SCHEMBL30831206 | 0.73 | SMN1; SMN2 (0.61) | DAGLASMN1; SMN2LMNARAB9AMAPT | |
| SCHEMBL1735989 | 0.70 | MAPT (0.55) | DAGLASMN1; SMN2LMNARAB9AMAPT | |
| SCHEMBL25789987 | 0.70 | HTT (0.66) | SMN1; SMN2LMNARAB9AMAPTKDM4E | |
| SCHEMBL27203418 | 0.70 | DAGLA (0.57) | DAGLASMN1; SMN2LMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492136-A2 | Retroviral protease inhibitors derived from 3-chloro-2-chloromethyl-1-propene | AMERICAN CYANAMID COMPANY (US) | 1992-07-01 | — | — | EP | disclosed |