Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336531 | 0.93 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2PPARGLTA4H | |
| SCHEMBL7348738 | 0.91 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2PPARGLTA4H | |
| SCHEMBL7342788 | 0.91 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2PPARGLTA4H | |
| SCHEMBL7345065 | 0.91 | HDAC8 (0.56) | NPC1RAB9ASMN1; SMN2PPARGLTA4H | |
| SCHEMBL7336782 | 0.90 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2PPARGLTA4H | |
| SCHEMBL7340426 | 0.89 | NOX1 (0.54) | NPC1RAB9ASMN1; SMN2PPARGLTA4H | |
| SCHEMBL7342497 | 0.86 | MMP9 (0.48) | NPC1RAB9ASMN1; SMN2PPARGLTA4H | |
| SCHEMBL7345567 | 0.86 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2PPARGLTA4H | |
| SCHEMBL7344073 | 0.85 | PPARG (0.62) | NPC1RAB9ASMN1; SMN2PPARGLTA4H | |
| SCHEMBL7344259 | 0.85 | MEN1 (0.52) | NPC1RAB9ASMN1; SMN2PPARGLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |